| Abbreviation | Definition |
|---|---|
| SE | Soldered Edition |
| SE | Splinter Edition |
| SE | Spyder Edition |
| SE | Substandard Edition |
| SE | Super Extendo |
| SEAD | Sanders Eating A Donut |
| SEAL | Some Escapees And Lunatics |
| SEAT | Society For Enlightenment And Transformation |
| SEC | Securing Entitlements For Crooks |
| SEC | See, Everyone Cheats |
| SEC | Surely Everybody's Cheating |
| SECRETS | Stop Even Considering Retelling Everthing Tom Said |
| SEED | Sith Elite Enforcer Division |
| SEEN | Seeing Eye And Elephant Network |
| SEGA | Semi-Educational Game Association |
| SEGA | Special Entertainment Games Association |
| SELF | Sentinent Engine Liberation Front |
| SEMA | Send Extra Money Away |
| SEN | Something Elephants Need |
| SENTOSA | So Expensive and Nothing to See Actually |