| Abbreviation | Definition |
|---|---|
| SEPTA | Slowly Eliminating Public Transportation Altogether |
| SERE | Sugar Extended Regular Expression |
| SERF | Snobbery Effacement And Reduction Factor |
| SERVICE | S = Say you are sorryE = Expedite the functionsR = Respond to the customerV = Victory to the customerI = Implement the thingsC = CorrespondenceE = Extend the out come |
| SERVICE | Say you are sorry, Expedite the functions, Respond to the customer, Victory to the customer, Implement the things, Correspondence, Extend the out come |
| SES | Smile Empty Soul |
| SET | Set Evaluates Things |
| SETI | Search for Easy Terrestrial Items |
| SETI | Search For Extra Transistors Inside |
| SEX | See Enter Extremely |
| SEX | Super Epic Xtravaganza |
| SEXY | Stupid Embarrassing Xanthous Yucky |
| SFB | Suffers From Belady's |
| SFFS | Satfire's Furcadia Fighting System |
| SFI | Stupid Friggon Idiot |
| SFL | Stunt For Life |
| SFN | Star Fangled Nut |
| SFR | Shadow Falcon Rangers |
| SGA | Smoking Goat Association |
| SGA | So Good Academy |