| Abbreviation | Definition |
|---|---|
| SDF | Social Democratic Front |
| SEC | State Enterprises Commission |
| SFO | Serious Fraud Office |
| SFO | Social Security and National Insurance Trust |
| SGMC | State Gold Mining Corporation |
| SIB | Special Investigations Board |
| SMA | Societas Missionum ad Afros |
| SMC | State Mining Companies |
| SMC | Supreme Military Council |
| SMCD | Supreme Military Council Decree |
| SME | Small and Medium Enterprises |
| SOERP | State-Owned Enterprise Reform Program |
| SPG | Society for the Propagation of the Gospel |
| SPLiT | Social Protection and Livelihood Technical Committee |
| SPP | Special Public Prosecutor |
| SRC | Students' Representative Council |
| SRID | Statistics, Research and Information Directorate |
| SSSG | Soils Science Society of Ghana |
| STAFAMS | State Farms Corporation |
| Supt | Superintendent |