| Abbreviation | Definition |
|---|---|
| SL | Safety Line |
| SLGA | Saskatchewan Liquor and Gaming Authority |
| SLLR | Street Legal Racing: Redline |
| SM3DW | Super Mario 3D World |
| SM64 | Super Mario 64 |
| SMA | Super Mario Advance |
| SMEG | Safe Marketing for Extreme Games |
| SMFC | Supreme Master First Class (CS:GO rank) |
| SMG | Soinc Min Games |
| SMG | Sub Machine Gun |
| SMG4 | Super Mario Glitchy 4 |
| SMGC | Social Media Gaming Consortium |
| SMGH | Salford and Manchester Gaming Haven |
| SML | Sticky Monster Lab |
| SMM2 | Super Mario Maker 2 |
| SMO | Super Mario Odyssey |
| SMOG | Secret Masters of Gaming |
| SMP | Survival Multi-Player |
| SMPL | Stan Minecraft PvP League |
| SMS | Super Mario Strikers |