| Abbreviation | Definition |
|---|---|
| MDT | Maintenance Demand Time |
| MDT | Mean Detonating Time |
| MDT | Mean Down Time |
| MDT | Measurement Descriptor Table |
| MDT | Mountain Daylight Time |
| MDTSCO | McDonnell Douglas Technical Services COmpany |
| MDUL | Missing Data Units List |
| ME | Main Engine |
| ME | Management Engineering |
| ME | Mid-Engined |
| ME | Miscellaneous Equipment |
| ME | Mission Engineer |
| MEA | Main Electronics Assembly |
| MEA | Main Engine Assembly |
| MEA | Materials Experiment Assembly |
| MEAR | Maintenance Engineering Analysis Request |
| MEAS | MEASurement |
| MEB | Main Electronics Box |
| MEBO | Main Engine Burnout |
| MEC | Main Engine Controller |