| Abbreviation | Definition |
|---|---|
| CONT | CONTinue |
| CONTAM | CONTAMinate |
| CONTIG | CONTIGuous |
| CONTR | CONTRol |
| CONV | CONVerter |
| COOP | COOPerative |
| COORD | COORDinate |
| COOS | Chemical Orbit-to-Orbit Satellite |
| COP | Contingency Operations Plan |
| COP | Continuous Operating Panel |
| COP | Co-Orbiting Platform |
| COPV | Composite Overwrapped Pressure Vessel |
| COQ | Certificate Of Qualification |
| CORE | Common Operational Research Equipment |
| COS | Carry-on Oxygen System |
| COS | Control Operating System |
| COS | Co-Orbiting Satellite |
| COS | Cosine |
| COS | Cosmic Origins Spectrograph |
| COSATI | Committee On Scientific and Technical Information |