| Abbreviation | Definition |
|---|---|
| SLS | Superb Level of Service |
| SLUT | Society for Liberation of Undone Trousers |
| SLUT | Spitting Like U Too |
| SMAC | Sid Meiers Alpha Centauri |
| SMACK | San Mateans Are Caring Kinks |
| SMART | Send the Mexicans Across the River Today |
| SMART | Stupidly Made Automobile that Runs Terribly |
| SMB | Same Microsoft Bull |
| SMB | So Many Breaches |
| SMB | Summer Means Beer |
| SMB | Super Monkey Ball |
| SMBFO | Suck My Big Fat One |
| SMBTSA | Send Me Back To Saudi Arabia |
| SMC | Silent Mack Club |
| SMD | Store My Ducks |
| SMDH | Serious Men Desire Hugs |
| SME | Sloppy Meat Eater |
| SMELLY | Society for Meaningless Evil Larceny Lying and Yelling |
| SMELLY | System Maintenance Entry Level Local Yaks |
| SMG | Some Manner of Greatness |