| Abbreviation | Definition |
|---|---|
| SOP | Science Operations Plan |
| SOP | Secondary Oxygen Pack |
| SOP | Senior Officer Present |
| SOP | Spacelab Opportunity Payload |
| SOP | Subsystem Operating Procedure |
| SOP | Subsystem Operating Program |
| SOP | Systems Operation Plan |
| SOPC | Shuttle Operations and Planning Center |
| SOPC | Shuttle Operations Planning Complex |
| SOR | Specification Operational Requirement |
| SOR | Stable Orbit Rendezvous |
| SORD | Systems Operations and Requirements Document |
| SORPTR | South Repeater |
| SORTIE | Short Term Mission |
| SOS | Serial Output Special |
| SOS | Source Of Supply |
| SOS | Stabilized Optical Sight |
| SOSA | Special Operations Support Area |
| SOSC | Space Operations Support Center |
| SOSM | Strap-On Solid Motor |