| Abbreviation | Definition |
|---|---|
| SOI | Saturn Orbit Insertion |
| SOI | Simultaneous Orbit Iteration |
| SOI | Solar Oscillations Investigation |
| SOIC | Small Outline Integrated Circuit |
| SOIS | Spacelab/Orbiter Interface Simulator |
| SOL | Science Operations Leader |
| SOL | Solar |
| SOL | Solenoid |
| SOLCON | Solar Constant |
| SOLN | Solution |
| SOLPAN | SOLar PANel |
| SOLSPEC | Solar Spectrum |
| SOM | Ship Operations Manager |
| SOM | Ship Operations Manager (NASA) |
| SOM | Spares Optimization Model |
| SOM | Standard Operating Manual |
| SOMD | Space Operations Mission Directorate |
| SOMF | Start of Minor Frame |
| SOMS | Shuttle Orbiter Medical System |
| SOOH | Spacecraft Orbital Operations Handbook |