| Abbreviation | Definition |
|---|---|
| SP-AF | Air Force STS (Space Transportation System) Liaison Office to Shuttle Projects Office directorate |
| SP-AF | Air Force STS Liaison Office (KSC Shuttle) |
| SP-AF | Air Force Support Office (KSC) |
| SPAH | Spacelab Payload Accommodations Handbook |
| SPAN | Space Physics Analysis Network |
| SPAN | Spacecraft Analysis |
| SPART | Space Research and Technology |
| SPAS | Shuttle Pallet Satellite |
| SPBK | Speed Brake |
| SPC | Shipping and Packing Cost |
| SPC | Shuttle Processing Contractor |
| SPC | Solar Protective Coating |
| SPC | Starting Point Code |
| SPC | Stored Program Command |
| SPC | Synoptic Properties Code |
| SPCC | STS Processing Control Center |
| SPCU | Simulation Process Control Unit |
| SPCW | Stored Program Command Word |
| SPD | Space Physics Division |
| SPD | Speed |