| Abbreviation | Definition |
|---|---|
| SPKR | Speaker |
| SPL | Scratch Pad Line |
| SPL | Serialized Parts List |
| SPL | Sound Pressure Level |
| SPL | Split Phase Level |
| SPL | System Programming Language |
| SP-LMO | Logistics Management Office (KSC) |
| SP-LMO | Logistics Management Office of the Shuttle Projects office directorate |
| SPLX | Simplex |
| SPLY | Supply |
| SPM | Software Programmers Manual |
| SPM | Space Switch Module |
| SPM | Subsystem Project Manager |
| SPM | Sun Photometer |
| SPMS | Special Purpose Manipulator System |
| SPN | Shuttle Project Notice (KSC) |
| SPN | Standard Precision Navigator |
| SPND | SusPeND |
| SPO | Shuttle Projects Office |
| SPO | Spare Parts Order |